Friday, January 23, 2009

Infertility Treatment

Treatment of infertility depends on the cause, how long you have been infertile, the age of the partners and many personal preferences.

Some causes of infertility can’t be corrected. However, a woman can still become pregnant with assisted reproductive technology or other procedures to restore fertility.

Male and female have to approach the problem of infertility. Some infertility problem can solve by medicine other times it may require surgery. If you are 35 or older, your doctor may recommend that you skip some of the steps couples usually take because your chances of having baby decrease with each passing year. Sometimes doctors do not find a problem with either the man or the woman and don’t know why a woman cannot get pregnant.

Treatment for female infertility:

Problems with ovulating
If your doctor finds that you have a problem with ovulating, they first recommend that you try the medicine clomiphene. This medicine stimulates your ovaries to release eggs, so it improves your chances of getting pregnant. It is often tried first because it is considered safe and effective. Then also you are not ovulating because of a condition called polycystic ovary syndrome (PCOS).
If this medicine is not reacting, typically hormone shots are the next medication tried.clomiphene increases your chance of having twins or triplets (especially twins), women who take hormonal injections are even more likely to have twins, triplets, or more babies.

Having intercourse two to three times a week may improve fertility. However, too-frequent ejaculation can lessen sperm quality. Sperm survive in the female reproductive tract for upto 72 hours, and an egg can be fertilized upto 24 hours after ovulation.

In general,they work like natural hormones- such as follicle- stimulating hormone (FSH) and lueteinizing hormone(LH) to trigger ovulation.

This drug is taken orally and stimulates ovulation in women who have pcos or other ovulatory disorders. It causes the pituary gland to release more FSH and LH, which stimulate the ovarian follicle containing egg.

Human menopausal gonadotropin, or hmg.
This injected medication is for women who don’t ovulate on their own due to the failure of the pituitary gland to stimulate ovulation. Unlike clomiphene, which stimulates the pituitary gland, hmg and other gonadotropins directly stimulate the ovaries. This drug contais both FSH and LH.
Follicle stimulating hormone,or FSH
FSH works by stimulating the ovaries to mature egg follicles
Human chronic gonadotrophin
Used in combination with clomiphene, hmg, FSH, this drug stimulates the follicle to release its egg.

Gonadotrophin- releasing hormone.
This treatment is for women with irregular ovulatory cycles or who ovulate prematurely -before the lead follicles is mature enough- during hmg treatment. Gn-RH analogs deliver constant Gn-RH to the pituitary gland, which alters hormone production, so that a doctor .

Letrozole
This drug is in a class of medications called aromatase inhibitors, which are approved for treatment of advanced breast cancer. Doctors sometimes prescribe letrozole for women who don’t ovulate on their own and who have’t responded to treatment with clomiphene citrate. Letrozole is not approved by the food and drug administration for inducing ovulation. The drug’s manufacturer has warned doctors not to use the drug for fertility purposes because of possible adverse health effects. These adverse effects may include birth defects and miscarriage.

Metformin:
This oral drug is taken to boost ovulation. It's used when insulin resistance is known or suspected cause of infertility. Insulin resistance may play a role in the development of PCOS.

Bromocriptine
This medication is for women, whose ovulation cycles are irregular due to elevated levels of prolactin, the hormone that stimulates milk production in new mothers. Bromocriptine inhibits prolactin production.

Treatment for male infertility
Other approaches that the male include treatment for:

General Sexual problems
Addressing impotence or premature ejaculation can improve fertility. Treatment for these problems often with medication or behavioral approaches.

Lack of sperm
If lack of sperm is suspected as the cause of man’s infertility, Surgery or hormones to correct the problem or use of assisted reproductive technology is sometimes possible. Varicose can often be surgically corrected. For blockage of the ejaculatory duct or in the case of retrograde ejaculation, sperm, can be taken directly from the testicles or recovered from the bladder and injected in to an egg in the laboratory settings.

Although pregnancy rates vary from center on the specific technique used but generally a 30% success rate can be expected.
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